Insulinoma (2)	

Symptoms frequently occur in the morning before breakfast and commonly include difficulty in waking. Nevertheless, contrary to common belief, an episode of reactive hypoglycaemia in response to the ingestion of a meal is often the earliest sign of disease in patients with insulinoma. 
Approximately fifteen per cent of all insulinomas are metastatic.

See also:
• Neuroglycopenia
• Diagnosis of Endogenous Hyperinsulinism
• Treatment of Endogenous Hyperinsulinism